Dermatol. vol no.4 supl.1 Rio de Janeiro July/Aug. Two male patients diagnosed with Zoon’s plasma cell balanitis, confirmed by biopsy, were subjected to. In , JJ Zoon first recognized balanitis circumscripta plasmacellularis (plasma cell balanitis) as an idiopathic, rare, benign penile dermatosis. Balanitis is inflammation of the glans penis. When the foreskin is also affected, it is termed Zoon’s balanitis also known as Balanitis Circumscripta Plasmacellularis or plasma cell balanitis (PCB) is Albertini JG, Holck DE, Farley MF ().

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Although it df described by Zoon inits etiopathogenesis still remains hypothetical. However, sometimes, it might be accompanied with symptoms such as pruritus, dysuria, pain, and burning sensation.

It is an idiopathic, chronic, benign inflammatory mucositis ba,anitis the genitalia that clinically presents as a solitary, shiny, well-defined erythematous plaque on the glans. Zoon’s plasma cell balanitis is a genital inflammatory dermatosis generally occurring in uncircumcised elderly males.

Balanitis – Wikipedia

Plasma cell balanitis treated with tacrolimus 0. Support Center Support Center. Histologically, benign conditions such as pemphigus vulgaris, flexural psoriasis, lichen planus, and Reiter’s disease may show features in common with ZB but lack the typical changes in the epidermis and dermal blood vessels. Torchia D, Cappugi P.


Pearce J, Fernando I. Histopathology of a biopsy made of one lesion on the glans, confirmed the bqlanitis of Zoon’s plasma cell balanitis. An overview and role of histopathology. Presentation of 15 patients, five treated with a carbon dioxide laser. First, CO 2 laser was used by Baldwin et al. Petersen CS, Thomsen K. Plasma cell balanitis of zoon bslanitis with topical tacrolimus 0. Plasma cell balanitis and vulvitis of Zoon. Furthermore, fixed drug eruption, allergic contact zopn, genital herpes, pemphigus vulgaris, flexural psoriasis, and Reiter’s disease should be differentiated from ZB.

Topical corticosteroids; note antibacterials and antifungals are of limited use. ZB has very distinct histopathological changes affecting both epidermis and dermis. Erythroplasia of Queyrat with Zoon’s balanitis: Lichen aureus of the glans penis as an expression of Zoon’s balanitis.

Regarding therapy, while circumcision is a highly effective treatment it is rejected by most patients. Some authors have also suggested that aseptic technique applied during circumcision, balanitks by regular cleaning during healing, might lead to improvement of the condition. We report the use of pimecrolimus, a homologue of tacrolimus, with good response. An effective therapy for Zoon balanitis.

Zoon balanitis: A comprehensive review

On the detailed scan of literature, there are four case reports, i. Zoon zlon cell balanitis: It is a benign condition of unknown etiology that tends to be asymptomatic.


Etiology and pathogenesis of this condition are still speculative. Inflammation of the glans penis and the preputial mucosa of a circumcised penis.

These are more common in cases with a dense infiltrate. Topical steroids preparations – There are mainly two studies zon by Yoganathan et al. The condition is relatively common in elderly men and presents clinically as well-demarcated, erythematous, shiny plaques on the glans, coronal sulcus or the inner surface of the foreskin. Benign plasma cell erythroplasia.

In addition to this, it is rather very important to differentiate this lesion from its clinical equivocal lesions such as erythroplasia of Queyrat, zoo and other inflammatory penile dermatoses, which has been discussed in this review.

Views Read Edit View history. Thus, there is a lack of supportive evidence for this hypothesis. Improvement was maintained over the 3month follow-up period Figure 5.