Hemolíticas. Keywords: Autoimmune hemolytic anemia, cold agglutinin disease, autoantibodies, treatment. Palabras clave: Anemia hemolitica autoinmune. Request PDF on ResearchGate | Protocolo diagnóstico de las anemias hemolíticas | The hemolytic anemias diagnosis remains a clinical challenge. Once a. Download Citation on ResearchGate | On Nov 1, , M. J. García Rodríguez and others published Protocolo diagnóstico de las anemias hemolíticas.

Author: Tobar Kazrall
Country: Pacific Islands
Language: English (Spanish)
Genre: Science
Published (Last): 20 September 2009
Pages: 173
PDF File Size: 11.45 Mb
ePub File Size: 12.65 Mb
ISBN: 134-5-73826-765-9
Downloads: 82744
Price: Free* [*Free Regsitration Required]
Uploader: Dalkree

[Anemias hemoliticas].

J Am Coll Cardiol. The dog was found to have persistently profound pallor, a highly regenerative hemolytic anemia and osteosclerosis.

Vet Clin Pathol 39, J Feline Med Surg 9, hemolitidas The clinical chemistry profile showed mild hyperbilirubinemia 0. Sickle cell chronic lung disease: The dog was treated presumptively with imidocarb dipropionate, doxycycline and iron supplements without clinical or hematological improvement and thus was referred. SCS Quadra 1, Bl. On blood smear evaluation anisocytosis, marked polychromasia, and normoblastosis were present.

Hemolkticas mechanism of action appears to be linked with the selective B-cell depletion and the lowering of autoantibody levels.

Indeed, many PK-deficient dogs are not diagnosed until one to several years of age, as the animals can often adapt well to the severe chronic anemia.


Regenerative anemias caused by blood loss or hemolysis. The dog had been previously transfused without blood typing and crossmatching. In the present case, similar values were observed over the entire observation period table 1although the PCV declined at some point to even lower levels.

Fax 1 E-mail: Nevertheless, a transfusion was deemed so desperately needed that blood from a “universal donor” was given. Some clinical improvement was observed within a day, but the PCV did not rise.

Anemias hemolíticas (1)

Pulmonary thromboembolism in beta-thalassemia intermedia: Pulmonary hypertension and cor pulmonale in the sickle hemoglobinopathies. Hereditary spherocytosis, thrombocytosis, and chronic pulmonary emboli: In order to prevent the further spread of this hemo,iticas other hereditary diseases, it is essential to recognize not only the affected animals, but also the carriers that hemolitics transmit the mutant allele to their offspring.

A variety of other immunosuppressive agents as well as splenectomy are used for refractory cases. Systemic fat embolism and pulmonary hypertension anekias sickle cell disease. Many animals with hemolytic anemia are initially misdiagnosed and treated for infectious diseases e. Moreover, in certain breeds, PK deficiency, just like other hereditary disorders and genetic predispositions to disease, may occur commonly due to the breeding of carrier animals HarveySewell et alGiger J Small Anim Pract 49, Hemolytic transfusion reactions in a dog with an alloantibody to a common antigen.


Anemiaz cholelithiasis and haemosiderosis in an anaemic pyruvate kinase-deficient Somali cat. As noted in this case, transient improvements and clinical stabilization can be observed.

Anemia Hemolítica Autoinmune | Medical City McKinney

Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes. Mol Med 16, Biochemical and molecular genetic tests have been developed for many diseases; however, their application as diagnostic tools for companion animals is still limited. Recurrent thromboembolic disease following splenectomy for pyruvate kinase deficiency. At the first examination, a leukocytosis may be normal for the young age or could have been associated with another concurrent illness, which may have been corrected by supportive treatment.

Oximetria de pulso noturna. Unfortunately, no information of the breeder or related dogs was available to further trace this dog’s ancestors and to identify related potential carrier or affected dogs. The dog was euthanized at 20 months of age due to the anekias of its clinical condition including anemia and blood incompatibility.